Evidence C · Moderate
A patented blend (Sphaeranthus indicus + Garcinia mangostana). Manufacturer studies show a reduction in waist circumference over 8 weeks.
Dose2 capsules/day (400 mg total)
Timing30 min before breakfast and dinner
FoodEmpty stomach (before the meal)
CautionStudies mostly sponsored
Proposed mechanism
- Inhibition of adipogenesis (the formation of new fat cells).
- Stimulation of lipolysis (the breakdown of existing fat).
- A specific focus on abdominal/visceral fat.
Evidence limitations
- Most of the RCTs are sponsored by the manufacturer (InterHealth/Lonza).
- Independent long-term studies are lacking.
- The real effect is modest — it does not replace diet + training.
Why take it before a meal
The supplement appears to work better when it is already in the system before nutrient intake, helping to modulate the postprandial metabolic response. 30 minutes beforehand is the typical window used in the studies.